产品货号:
Z16624
中文名称:
GRB10抗体
英文名称:
Anti-GRB10 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GRB10 Antibody |
指标别名 | Grb 10;GRB IR;GRB10;GRB10 adapter protein;GRBIR;IRBP;KIAA0207;MEG1;RSS |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IF |
基因名称 | GRB10 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10.The immunogen is located within amino acids 440 - 490 of GRB10. |
计算分子量 | 67kDa |
成分 | GRB10 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | GRB10 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes.GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors.Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression.GRB10 can also interact with the L isoform of the proapoptotic protein Bim.This gene is imprinted in a highly isoform- and tissue-specific manner,with expression observed from the paternal allele in the brain,and from the maternal allele in the placental trophoblasts. |
Uniprot ID | Q13322 |
基因名全称 | Growth factor receptor-bound protein 10 |
蛋白名全称 | Growth factor receptor-bound protein 10 |
推荐稀释比 | GRB10 antibody can be used for detection of GRB10 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunofluorescence starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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